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1

A unique inhibitor binding site in ERK1/2 is associated with slow binding kinetics

Chaikuad, Apirat, M C Tacconi, Eliana, Zimmer, Jutta, Liang, Yanke, Gray, Nathanael S, Tarsounas, Madalena, Knapp, Stefan

Journal:

Nature Chemical Biology

Year:

2014

Language:

english

File:

PDF, 4.50 MB

english, 2014

2

The antitumorigenic roles of BRCA1âBARD1 in DNA repair and replication

Tarsounas, Madalena, Sung, Patrick

Journal:

Nature Reviews Molecular Cell Biology

Year:

2020

Language:

english

File:

PDF, 1.98 MB

english, 2020

3

PLU-1, a transcriptional repressor and putative testis-cancer antigen, has a specific expression and localisation pattern during meiosis

Bente Madsen, Madalena Tarsounas, JoyM. Burchell, Debbie Hall, Richard Poulsom, Joyce Taylor-Papadimitriou

Journal:

Year:

2003

Language:

english

File:

PDF, 624 KB

english, 2003

4

Rad51 immunocytology in rat and mouse spermatocytes and oocytes

Peter B. Moens, David J. Chen, Zhiyuan Shen, Nadine Kolas, Madalina Tarsounas, Henry H. Q. Heng, Barbara Spyropoulos

Journal:

Year:

1997

Language:

english

File:

PDF, 605 KB

english, 1997

5

The association of ATR protein with mouse meiotic chromosome cores

Peter B. Moens, Madalena Tarsounas, Takashi Morita, Toshiyuki Habu, Scott T. Rottinghaus, Raimundo Freire, Stephen P. Jackson, Carrolee Barlow, Anthony Wynshaw-Boris

Journal:

Year:

1999

Language:

english

File:

PDF, 500 KB

english, 1999

6

Telomere regulation and function during meiosis

Manos Siderakis, Madalena Tarsounas

Journal:

Chromosome Research

Year:

2007

Language:

english

File:

PDF, 390 KB

english, 2007

7

Mammalian Rap1 controls telomere function and gene expression through binding to telomeric and extratelomeric sites

Martinez, Paula, Thanasoula, Maria, Carlos, Ana R., Gómez-López, Gonzalo, Tejera, Agueda M., Schoeftner, Stefan, Dominguez, Orlando, Pisano, David G., Tarsounas, Madalena, Blasco, Maria A.

Journal:

Nature Cell Biology

Year:

2010

Language:

english

File:

PDF, 1.20 MB

english, 2010

8

BRCA2-dependent and independent formation of RAD51 nuclear foci

Tarsounas, Madalena, Davies, Derek, West, Stephen C

Journal:

Year:

2003

Language:

english

File:

PDF, 364 KB

english, 2003

9

Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest

Constantinou, Angelos, Tarsounas, Madalena, Karow, Julia K., Brosh, Robert M., Bohr, Vilhelm A., Hickson, Ian D., West, Stephen C.

Journal:

Year:

2000

Language:

english

File:

PDF, 305 KB

english, 2000

10

p53 Prevents Entry into Mitosis with Uncapped Telomeres

Maria Thanasoula, Jose Miguel Escandell, Paula Martinez, Sophie Badie, Purificacion Muñoz, María A. Blasco, Madalena Tarsounas

Journal:

Current Biology

Year:

2010

Language:

english

File:

PDF, 1001 KB

english, 2010

11

The genomic structure of SYCP3, a meiosis-specific gene encoding a protein of the chromosome core

Roberto J. Botelho, Lisa DiNicolo, Nora Tsao, Angelo Karaiskakis, Madalena Tarsounas, Peter B. Moens, Ronald E. Pearlman

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

2001

Language:

english

File:

PDF, 539 KB

english, 2001

12

CLIP-50 Immunolocalization during Mouse Spermiogenesis Suggests a Role in Shaping the Sperm Nucleus

Madalena Tarsounas, Ronald E. Pearlman, Peter B. Moens

Journal:

Developmental Biology

Year:

2001

Language:

english

File:

PDF, 635 KB

english, 2001

13

TPP1 Is Required for TERT Recruitment, Telomere Elongation during Nuclear Reprogramming, and Normal Skin Development in Mice

Agueda M. Tejera, Martina Stagno d'Alcontres, Maria Thanasoula, Rosa M. Marion, Paula Martinez, Chunyan Liao, Juana M. Flores, Madalena Tarsounas, Maria A. Blasco

Journal:

Developmental Cell

Year:

2010

Language:

english

File:

PDF, 2.50 MB

english, 2010

14

RAD51 paralogs: Roles in DNA damage signalling, recombinational repair and tumorigenesis

Natsuko Suwaki, Kerstin Klare, Madalena Tarsounas

Journal:

Seminars in Cell & Developmental Biology

Year:

2011

Language:

english

File:

PDF, 901 KB

english, 2011

15

Telomere Maintenance Requires the RAD51D Recombination/Repair Protein

Madalena Tarsounas, Purificacı́on Muñoz, Andreas Claas, Phillip G Smiraldo, Douglas L Pittman, Marı́a A Blasco, Stephen C West

Journal:

Year:

2004

Language:

english

File:

PDF, 621 KB

english, 2004

16

ATM/ATR checkpoint activation downregulates CDC25C to prevent mitotic entry with uncapped telomeres

Thanasoula, Maria, Escandell, Jose Miguel, Suwaki, Natsuko, Tarsounas, Madalena

Journal:

The EMBO Journal

Year:

2012

Language:

english

File:

PDF, 1.20 MB

english, 2012

17

Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice

Martinez, P., Thanasoula, M., Munoz, P., Liao, C., Tejera, A., McNees, C., Flores, J. M., Fernandez-Capetillo, O., Tarsounas, M., Blasco, M. A.

Journal:

Genes & Development

Year:

2009

Language:

english

File:

PDF, 2.46 MB

english, 2009

18

Genomes and G-Quadruplexes: For Better or for Worse

Tarsounas, Madalena, Tijsterman, Marcel

Journal:

Journal of Molecular Biology

Year:

2013

Language:

english

File:

PDF, 468 KB

english, 2013

19

RAD51 and DMC1 Form Mixed Complexes Associated with Mouse Meiotic Chromosome Cores and Synaptonemal Complexes

Madalena Tarsounas, Takashi Morita, Ronald E. Pearlman and Peter B. Moens

Journal:

The Journal of Cell Biology

Year:

1999

Language:

english

File:

PDF, 4.24 MB

english, 1999

20

RAD51C Facilitates Checkpoint Signaling by Promoting CHK2 Phosphorylation

Sophie Badie, Chunyan Liao, Maria Thanasoula, Paul Barber, Mark A. Hill and Madalena Tarsounas

Journal:

The Journal of Cell Biology

Year:

2009

Language:

english

File:

PDF, 3.86 MB

english, 2009

21

[Current Topics in Developmental Biology] Volume 51 || Checkpoint and DNA-repair proteins are associated with the cores of mammalian meiotic chromosomes

Tarsounas, Madalena

Year:

2001

Language:

english

File:

PDF, 243 KB

english, 2001

22

Introduction

Sjögren, Camilla, Tarsounas, Madalena, Bartek, Jiri, Höög, Christer

Journal:

Experimental Cell Research

Year:

2014

Language:

english

File:

PDF, 276 KB

english, 2014

23

How homologous recombination maintains telomere integrity

Tacconi, Eliana M. C., Tarsounas, Madalena

Journal:

Year:

2015

Language:

english

File:

PDF, 735 KB

english, 2015

24

BRCA1 and CtIP promote alternative non-homologous end-joining at uncapped telomeres

Badie, S., Carlos, A. R., Folio, C., Okamoto, K., Bouwman, P., Jonkers, J., Tarsounas, M.

Journal:

The EMBO Journal

Year:

2015

Language:

english

File:

PDF, 978 KB

english, 2015

25

It's getting HOT at telomeres

Tarsounas, Madalena

Journal:

The EMBO Journal

Year:

2013

Language:

english

File:

PDF, 110 KB

english, 2013

26

Protein-protein interactions in the synaptonemal complex.

Tarsounas, M., Pearlman, R. E., Gasser, P. J., Park, M. S., Moens, P. B.

Journal:

Molecular Biology of the Cell

Year:

1997

Language:

english

File:

PDF, 2.05 MB

english, 1997

27

RAD51 localization and activation following DNA damage

Tarsounas, M., Davies, A. A., West, S. C.

Journal:

Philosophical Transactions Biological Sciences

Year:

2004

Language:

english

File:

PDF, 2.34 MB

english, 2004

28

RAD51 and DMC1 Form Mixed Complexes Associated with Mouse Meiotic Chromosome Cores and Synaptonemal Complexes

Journal:

The Journal of Cell Biology

Year:

1999

Language:

english

File:

PDF, 674 KB

english, 1999

29

Human and mouse homologs of Schizosaccharomyces pombe rad1+ and Saccharomyces cerevisiae RAD17: linkage to checkpoint control and mammalian meiosis

Freire, R., Murguia, J. R., Tarsounas, M., Lowndes, N. F., Moens, P. B., Jackson, S. P.

Journal:

Genes & Development

Year:

1998

Language:

english

File:

PDF, 1.71 MB

english, 1998

30

Identification of the mouse β`-COP golgi component as a spermatocyte autoantigen in scleroderma and mapping of its gene Copb2 to mouse Chromosome 9

Tarsounas, M., Heng, H.H.Q., Ye, C.J., Pearlman, R.E., Moens, P.B.

Journal:

Cytogenetic and Genome Research

Year:

1999

Language:

english

File:

PDF, 726 KB

english, 1999

31

Role of RAD51C and XRCC3 in Genetic Recombination and DNA Repair

Liu, Y., Tarsounas, M., O'Regan, P., West, S. C.

Journal:

Journal of Biological Chemistry

Year:

2007

Language:

english

File:

PDF, 856 KB

english, 2007

32

RAD51C facilitates checkpoint signaling by promoting CHK2 phosphorylation

Badie, S., Liao, C., Thanasoula, M., Barber, P., Hill, M. A., Tarsounas, M.

Journal:

The Journal of Cell Biology

Year:

2009

Language:

english

File:

PDF, 4.45 MB

english, 2009

33

BRCA1 and CtIP promote alternative non-homologous end-joining at uncapped telomeres

Badie, S., Carlos, A. R., Folio, C., Okamoto, K., Bouwman, P., Jonkers, J., Tarsounas, M.

Journal:

The EMBO Journal

Year:

2015

Language:

english

File:

PDF, 141 KB

english, 2015

34

Recombination at Mammalian Telomeres: An Alternative Mechanism for Telomere Protection and Elongation

Tarsounas, Madalena, West, Stephen C.

Journal:

Year:

2005

Language:

english

File:

PDF, 245 KB

english, 2005

35

FANCD2 limits replication stress and genome instability in cells lacking BRCA2

Michl, Johanna, Zimmer, Jutta, Buffa, Francesca M, McDermott, Ultan, Tarsounas, Madalena

Journal:

Nature Structural and Molecular Biology

Year:

2016

Language:

english

File:

PDF, 1.48 MB

english, 2016

36

Replicating and Reshaping DNA: A Celebration of the Jubilee of the Double Helix || RAD51 Localization and Activation Following DNA Damage

Madalena Tarsounas, Adelina A. Davies and Stephen C. West

Journal:

Philosophical Transactions Biological Sciences

Year:

2004

Language:

english

File:

PDF, 1.45 MB

english, 2004

37

The repair of double-strand breaks in human cells

West, S. C., Baillot, A., Chappell, C., Constantinou, A., Davies, A., Van Dyck, E., Hanakahi, L., Masson, J. Y., McIlwraith, M., Parsons, C. A., Tarsounas, M.

Journal:

Biochemical Society Transactions

Year:

2000

Language:

english

File:

PDF, 154 KB

english, 2000

38

Lead Discovery of Dual G-Quadruplex Stabilizers and Poly(ADP-ribose) Polymerases (PARPs) Inhibitors: A New Avenue in Anticancer Treatment

Salvati, Erica, Botta, Lorenzo, Amato, Jussara, Di Leva, Francesco Saverio, Zizza, Pasquale, Gioiello, Antimo, Pagano, Bruno, Graziani, Grazia, Tarsounas, Madalena, Randazzo, Antonio, Novellino, Ettor

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.01 MB

english, 2017

39

Interplay between Fanconi anemia and homologous recombination pathways in genome integrity

Michl, Johanna, Zimmer, Jutta, Tarsounas, Madalena

Journal:

The EMBO Journal

Year:

2016

Language:

english

File:

PDF, 464 KB

english, 2016

40

Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells

Schoonen, Pepijn M., Talens, Francien, Stok, Colin, Gogola, Ewa, Heijink, Anne Margriet, Bouwman, Peter, Foijer, Floris, Tarsounas, Madalena, Blatter, Sohvi, Jonkers, Jos, Rottenberg, Sven, van Vugt,

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 1.89 MB

english, 2017

41

MUS81 nuclease activity is essential for replication stress tolerance and chromosome segregation in BRCA2-deficient cells

Lai, Xianning, Broderick, Ronan, Bergoglio, Valérie, Zimmer, Jutta, Badie, Sophie, Niedzwiedz, Wojciech, Hoffmann, Jean-Sébastien, Tarsounas, Madalena

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 1.52 MB

english, 2017

42

Corrigendum: MUS81 nuclease activity is essential for replication stress tolerance and chromosome segregation in BRCA2-deficient cells

Lai, Xianning, Broderick, Ronan, Bergoglio, Valérie, Zimmer, Jutta, Badie, Sophie, Niedzwiedz, Wojciech, Hoffmann, Jean-Sébastien, Tarsounas, Madalena

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 677 KB

english, 2017

43

Radiolabeled oligonucleotides targeting the RNA subunit of telomerase inhibit telomerase and induce DNA damage in telomerase-positive cancer cells

Jackson, Mark R, Bavelaar, Bas M, Waghorn, Philip A, Gill, Martin R, El-Sagheer, Afaf H, Brown, Tom, Tarsounas, Madalena, Vallis, Katherine A

Journal:

Cancer Research

Year:

2019

Language:

english

File:

PDF, 5.11 MB

english, 2019

44

Radiolabeled oligonucleotides targeting the RNA subunit of telomerase inhibit telomerase and induce DNA damage in telomerase-positive cancer cells

Jackson, Mark R, Bavelaar, Bas M, Waghorn, Philip A, Gill, Martin R, El-Sagheer, Afaf H, Brown, Tom, Tarsounas, Madalena, Vallis, Katherine A

Journal:

Cancer Research

Year:

2019

File:

PDF, 5.11 MB

2019

45

DNA Damage and Cancer Immunotherapy: a STING in the Tale

ReislÃ¤nder, Timo, Groelly, Florian J., Tarsounas, Madalena

Journal:

Year:

2020

File:

PDF, 653 KB

2020